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Causes
Of Polycystic Kidneys?
Have you or someone you know been diagnosed with
Polycystic Kidney Disease (PKD)? If so, you may be wondering what
the causes of polycystic kidneys are. To answer this question is to
understand that PKD is a genetic disease brought about by the
transfer of an abnormal, mutated gene from one or both of the
parents. Well, this is a slight lie - there is a rare form of the
disease which can be gotten from old age and a pattern of dialysis,
amongst other reasons. There are two forms of the disease which are
genetic - autosomal dominant PKD and autosomal recessive
PKD.
To understand the cause of polycystic kidneys, it is worthwhile
to take a closer look at these 2 forms of PKD. This first form we
will discuss is autosomal dominant PKD which affects around 90% of
the 7 million people worldwide who have this life-threatening
disease. In order to inherit the abnormal gene, the child need only
receive the abnormal gene from the one affected parent. This means
they have a 1 in 2 chance of inheriting the gene and hence
suffering from autosomal dominant PKD in mid to late life, when it
is likely to occur.
The other, rarer from of genetic PKD is autosomal recessive PKD.
This is the childhood form of the disease which afflicts 1 in
20,000 people. In this type of PKD, the child must inherit the
abnormal gene from both affected parents, giving them a 1 in 4
chance of suffering from the disease. Now that the gene that causes
PKD has been discovered, couples can undergo family planning
counseling to discuss the possibility if their offspring developing
PKD.
Hopefully this article clears up what the causes of polycystic
kidneys are. Of course, if you feel you may be experiencing any of
the common symptoms such as blood in the urine, urinary tract
infections and abdomen/lower back pain it is highly recommended to
visit your doctor.
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